Levodopa plus carbidopa before physiotherapy increased motor recovery after stroke.

Intervention Patients were allocated to levodopa, 100 mg, plus carbidopa (n=26) or to placebo (n=27) given daily in the morning > 30 minutes before the physiotherapy session for 3 weeks. For the next 3 weeks, both groups had 1 hour of daily physiotherapy from Monday to Friday without the allocated treatment. 1 week before and during the study, all patients stopped receiving any drugs that affected norepinephrine concentrations.